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抗体 > 多克隆抗体 > NF2 Antibody
  • 产品类型:
    Polyclonal Antibody
  • 产品名称:

    NF2 Antibody

  • 货号:
    CSB-PA015741LA01HU
  • 规格:
    ¥1200
  • 别名:
    ACN antibody; BANF antibody; Bilateral acoustic neuroma antibody; MERL_HUMAN antibody; Merlin antibody; Moesin ezrin radixin like protein antibody; Moesin ezrin radizin like antibody; Moesin-ezrin-radixin-like protein antibody; Neurofibromatosis 2 antibody; Neurofibromatosis type 2 antibody; Neurofibromatosis2 antibody; Neurofibromin 2 antibody; Neurofibromin-2 antibody; Neurofibromin2 antibody; NF 2 antibody; Nf2 antibody; SCH antibody; Schwannomerlin antibody; Schwannomin antibody
  • 种属:
    Homo sapiens (Human)
  • 免疫原:
    Recombinant Human Merlin protein (230-414AA)
  • 宿主:
    Rabbit
  • 种属反应性:
    Human, Mouse
  • 应用范围:
    ELISA, WB, IHC, IF; Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200
  • 背景:
    Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 标记方式:
    Non-conjugated
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 图片:

    Western Blot

    Positive WB detected in: HEK293 whole cell lysate, Jurkat whole cell lysate, MCF-7 whole cell lysate, NIH/3T3 whole cell lysate

    All lanes: NF2 antibody at 2.6μg/ml

    Secondary

    Goat polyclonal to rabbit IgG at 1/50000 dilution

    Predicted band size: 70, 73, 60, 65, 64, 31, 66, 20, 25 kDa

    Observed band size: 70, 73 kDa

    Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA015741LA01HU at dilution of 1:100

    Immunofluorescent analysis of Hela cells using CSB-PA015741LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • 说明书:
  • Accession No。:
  • 指标名称:
    NF2
  • 研究领域:
    Neuroscience