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抗体 > 多克隆抗体 > HSPD1 Antibody
  • 产品类型:
    Polyclonal Antibody
  • 产品名称:

    HSPD1 Antibody

  • 货号:
    CSB-PA010847LA01HU
  • 规格:
    ¥1200
  • 别名:
    60 kDa chaperonin antibody; 60 kDa heat shock protein; mitochondrial antibody; CH60_HUMAN antibody; Chaperonin 60 antibody; Chaperonin; 60-KD antibody; CPN60 antibody; fa04a05 antibody; GROEL antibody; heat shock 60kDa protein 1 (chaperonin) antibody; Heat shock protein 1 (chaperonin) antibody; Heat shock protein 60 antibody; Heat shock protein 65 antibody; heat shock protein family D (Hsp60) member 1 antibody; HLD4 antibody; Hsp 60 antibody; HSP 65 antibody; HSP-60 antibody; HSP60 antibody; HSP65 antibody; HSPD1 antibody; HuCHA60 antibody; Mitochondrial matrix protein P1 antibody; P60 lymphocyte protein antibody; short heat shock protein 60 Hsp60s1 antibody; SPG13 antibody
  • 种属:
    Homo sapiens (Human)
  • 免疫原:
    Recombinant Human 60 kDa heat shock protein, mitochondrial protein (225-573AA)
  • 宿主:
    Rabbit
  • 种属反应性:
    Human, Mouse
  • 应用范围:
    ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500
  • 背景:
    Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:1346131, PubMed:11422376). The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable).
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 标记方式:
    Non-conjugated
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式:
    Liquid
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 图片:

    Western Blot

    Positive WB detected in: 293 whole cell lysate, HepG2 whole cell lysate, 293T whole cell lysate, K562 whole cell lysate, Mouse brain tissue, Mouse liver tissue

    All lanes: HSPD1 antibody at 1:2000

    Secondary

    Goat polyclonal to rabbit IgG at 1/50000 dilution

    Predicted band size: 62, 18 kDa

    Observed band size: 62 kDa

    IHC image of CSB-PA010847LA01HU diluted at 1:300 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • 说明书:
  • Accession No。:
  • 指标名称:
    HSPD1
  • 研究领域:
    Tags & Cell Markers