吉利彩票投注

Human Fibrinogen-like protein 1(FGL1) ELISA kit

Datasheet
  • 中文名称:
    Human Fibrinogen-like protein 1(FGL1) ELISA kit
  • 货号:
    CSB-EL008653HU
  • 规格:
    96T
  • 价格:
    3600
  • 其他:

产品详情

  • 基因名:
    FGL1
  • 别名:
    FGL 1 ELISA Kit; Fgl1 ELISA Kit; FGL1_HUMAN ELISA Kit; Fibrinogen like 1 ELISA Kit; Fibrinogen like protein 1 ELISA Kit; Fibrinogen related protein 1 ELISA Kit; Fibrinogen-like protein 1 ELISA Kit; Hepassocin ELISA Kit; Hepatocellular carcinoma related sequence ELISA Kit; Hepatocyte derived fibrinogen related protein 1 ELISA Kit; Hepatocyte-derived fibrinogen-related protein 1 ELISA Kit; HFREP 1 ELISA Kit; HFREP-1 ELISA Kit; HFREP1 ELISA Kit; HP 041 ELISA Kit; HP-041 ELISA Kit; HP041 ELISA Kit; LFIRE 1 ELISA Kit; LFIRE-1 ELISA Kit; LFIRE1 ELISA Kit; Liver fibrinogen related protein 1 ELISA Kit; Liver fibrinogen-related protein 1 ELISA Kit; MFIRE 1 ELISA Kit; MGC108569 ELISA Kit; MGC12455 ELISA Kit; MGC37822 ELISA Kit; OTTHUMP00000122468 ELISA Kit
  • 缩写:
    FGL1
  • Uniprot No.:
  • 种属:
    Homo sapiens (Human)
  • 样本类型:
    serum, plasma, tissue homogenates
  • 检测范围:
    23.5 pg/mL-1500 pg/mL
  • 灵敏度:
    5.86 pg/mL
  • 反应时间:
    1-5h
  • 样本体积:
    50-100ul
  • 检测波长:
    450 nm
  • 研究领域:
    Cardiovascular
  • 测定原理:
    quantitative
  • 测定方法:
    Sandwich
  • 精密度:
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 线性度:
    To assess the linearity of the assay, samples were spiked with high concentrations of Human FGL1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:20Average %89
    Range %84-94
    1:40Average %87
    Range %82-93
    1:80Average %95
    Range %89-99
    1:160Average %98
    Range %92-104
  • 回收率:
    The recovery of Human FGL1 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9388-97
    EDTA plasma (n=4)8782-92
  • 标准曲线:
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    15002.758 2.645 2.702 2.607
    7502.107 2.296 2.202 2.107
    3751.601 1.524 1.563 1.468
    187.50.867 0.845 0.856 0.761
    940.475 0.483 0.479 0.384
    470.317 0.304 0.311 0.216
    23.50.181 0.176 0.179 0.084
    00.095 0.094 0.095
  • 货期:
    7-14 working days

引用文献

  • Wu HT,FASEB J,2019
  • Huang R L, et al,Biofactors,2019
  • Han NK, et al,Cells,2019

靶点详情

  • 功能:
    Has hepatocyte mitogenic activity.
  • 基因功能参考文献:
    1. FGL1 promotes invasion and metastasis of gastric cancer and is associated with poor prognosis.
    2. findings highlight the crucial role of HFREP1 in insulin resistance and diabetes, and provide a potential strategy and biomarker for developing therapeutic approaches to combat these diseases.
    3. Hepassocin plays an important role in non-alcoholic fatty liver disease and induces hepatic lipid accumulation through an ERK1/2-dependent pathway.
    4. Here, the application of small ubiquitin-related modifier (SUMO) fusion technology in combination with four different chaperone teams on the soluble expression of recombinant HPS protein was explored and analyzed.
    5. Findings suggest that hepassocin promotes hepatic cell line L02 cells proliferation via an autocrine mechanism and inhibits HCC cells proliferation by an intracrine pathway.
    6. data demonstrated that liver-specific gene LFIRE-1/HFREP-1 was frequently downregulated and might possess growth suppressor activity in HCC
    7. HFREP-1 in plasma almost completely bound to the fibrin matrix during clot formation
    8. The enhancement of FGL1 levels in vitro by IL-6 and its induction after turpentine oil injection suggest that it is an acute phase reactant.
    9. HNF1 binding site and HNF1alpha are critical to liver-specific expression of HPS, and down-regulation or loss of HNF1alpha causes, at least in part, the transcriptional down-regulation of HPS in HCC.

    显示更多

    收起更多

  • 亚细胞定位:
    Secreted
  • 组织特异性:
    Liver specific.
  • 数据库链接:

    HGNC:

    OMIM:

    KEGG:

    STRING:

    UniGene:



博发彩票开户 博发彩票APP下载 博发彩票登陆 迪士尼彩乐园官方网址 桔子彩票开奖 帝皇彩票登陆 上海时时乐 福建泰顺棋牌俱乐部 吉利彩票投注 吉利彩票计划

博发彩票开户 博发彩票APP下载 博发彩票登陆 迪士尼彩乐园官方网址 桔子彩票开奖 帝皇彩票登陆 上海时时乐 福建泰顺棋牌俱乐部 吉利彩票投注 吉利彩票计划